PROMPT: Protein Mapping and Comparison Tool

PROMPT is a platform independent system for retrieval, analysis, mapping and comparison of protein sets. It allows easy mapping of different types of sequence identifiers, automatical data retrieval and integration, a multitude of analysis and comparison algorithms and a full-featured easy to use graphical user interface (GUI) application with an integrated help-system. Moreover exhaustive statistical tests are conducted in appropriate cases automatically or could be performed manually. Furthermore all analysis results can be viewed or visualized with one mouse-click and exported in various formats e.g. to Microsoft Excel. Additionally all methods can be used easily in your own Java code or with powerful beanshell scripting in own scripts, a pipeline or grid systems.


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Case Studies

New: Web based Fast Mapping to large databases by F. Hager


Publications that cite PROMPT

Protein abundance profiling of the Escherichia coli cytosol
Ishihama Y, Schmidt T, Rappsilber J, et al.
BMC GENOMICS Volume: 9 Article Number: 102 Published: FEB 27 2008

OREST - Online resource for EST analysis
Wägele B, Schmidt T, Ruepp A, Mewes HW
NUCLEIC ACIDS RESEARCH, in press, 2008

An approach to handling and interpretation of ambiguous data in transcriptome and proteome comparisons
Irmler M, Hartl D, Schmidt T, et al.
PROTEOMICS Volume: 8 Issue: 6 Pages: 1165-1169 Published: MAR 2008

The fungus Ustilago maydis and humans share disease-related proteins that are not found in Saccharomyces cerevisiae
Munsterkotter M, Steinberg G
BMC GENOMICS Volume: 8 Article Number: 473 Published: DEC 20 2007

SIMAPstructuring the network of protein similarities
Rattei T, Tischler P, Arnold R, et al.
NUCLEIC ACIDS RESEARCH Volume: 36 Special Issue: Sp. Iss. SI Pages: D289-D292 Published: JAN 2008

The Protein Identifier Cross-Referencing (PICR) service: reconciling protein identifiers across multiple source databases
Cote RG, Jones P, Martens L, et al.
BMC BIOINFORMATICS Volume: 8 Article Number: 401 Published: OCT 18 2007

Bioinformatics for study of autoimmunity.
Petrovsky N, Brusic V.
AUTOIMMUNITY. 2006 Dec;39(8):635-43.

PEDANT genome database: 10 years online.
Riley ML, Schmidt T, Artamonova II, Wagner C, Volz A, Heumann K, Mewes HW, Frishman D.
NUCLEIC ACIDS RESEARCH 2006 Dec 5
Web-version, PDF-screen, PDF-print, About the journal

TOOLbox - PROMPT for comparisons,
Vol. 5, No. 9: September 2006; pp 2072–2073;
JOURNAL OF PROTEOME RESEARCH
(2006)
Web-version, PDF-screen, PDF-print, About the journal

PROMPT reference

Schmidt, T., Frishman, D. (2006), PROMPT: a protein mapping and comparison tool,
BMC Bioinformatics 2006, 7:331; Link